BI 2852 FL
Product Specifications
CAS Number
2762758-95-0
Target
Ras, Kras
Related Pathways
MAPK
Bioactivity
BI 2852 FL is a cell-permeable bioluminescence resonance energy transfer (BRET) fluorescent probe targeting the pan-RAS type. It is synthesized by conjugating a fluorophore with a derivative of the reversible SI/II-P KRAS inhibitor, BI 2852. BI 2852 FL is employed in a competitive BRET format to quantify the binding of SII-P to multimeric RAS complexes within living cells.
Smiles
O=C1NC(C2=C(CNCC3=CC4=C(C=CN4CC5=NC=CN5CCCCC(NCCOCCOCCOCCNC(CCC6=CC=C7C=C8C=CC(C9=CC=CN9)=[N+]8[B-](F)(N76)F)=O)=O)C=C3)NC%10=C2C=CC=C%10)C%11=CC(O)=CC=C1%11
Molecular Formula
C59H64BF2N11O7
Molecular Weight
1088.02
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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