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LXG6403

Product Specifications

CAS Number

315705-04-5

Target

Others, ROS, Apoptosis, FAK, Lipoxygenase

Related Pathways

Immunology/Inflammation, Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Metabolism, Others

Bioactivity

LXG6403 is a powerful dual-thiazole LOX cell activity inhibitor with an IC50 of 1.3 μM. It exhibits anticancer properties by restructuring the extracellular matrix, enhancing the penetration of chemotherapeutic drugs, inducing reactive oxygen species (ROS) production, and promoting cell death mediated by DNA damage, thereby overcoming chemotherapy resistance in triple-negative breast cancer.

Smiles

O=C(NC1=CC=C(C=C1)NC2=NC(=CS2)C=3SC(=NC3C)N)C

Molecular Formula

C15H15N5OS2

Molecular Weight

345.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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