LXG6403
Product Specifications
CAS Number
315705-04-5
Target
Others, ROS, Apoptosis, FAK, Lipoxygenase
Related Pathways
Immunology/Inflammation, Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Metabolism, Others
Bioactivity
LXG6403 is a powerful dual-thiazole LOX cell activity inhibitor with an IC50 of 1.3 μM. It exhibits anticancer properties by restructuring the extracellular matrix, enhancing the penetration of chemotherapeutic drugs, inducing reactive oxygen species (ROS) production, and promoting cell death mediated by DNA damage, thereby overcoming chemotherapy resistance in triple-negative breast cancer.
Smiles
O=C(NC1=CC=C(C=C1)NC2=NC(=CS2)C=3SC(=NC3C)N)C
Molecular Formula
C15H15N5OS2
Molecular Weight
345.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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