5-Hydroxypropafenone hydrochloride
Product Specifications
CAS Number
86383-32-6
Target
Others, Potassium Channel
Related Pathways
Membrane transporter/Ion channel, Others
Bioactivity
5-Hydroxypropafenone, an active metabolite of propafenone, inhibits transient outward potassium current (Ito) in isolated human atrial myocytes with an IC50 of 1.5 μM. In vivo, it increases the atrial effective refractory period in dogs at doses of 0.5, 1, and 2 mg/kg.
Smiles
Cl.O=C(C1=CC(O)=CC=C1OCC(O)CNCCC)CCC=2C=CC=CC2
Molecular Formula
C21H28ClNO4
Molecular Weight
393.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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