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5-Hydroxypropafenone hydrochloride

Product Specifications

Target

Others|||Potassium Channel

Related Pathways

Membrane transporter/Ion channel|||Others

Bioactivity

5-Hydroxypropafenone, an active metabolite of propafenone, inhibits transient outward potassium current (Ito) in isolated human atrial myocytes with an IC50 of 1.5 µM. In vivo, it increases the atrial effective refractory period in dogs at doses of 0.5, 1, and 2 mg/kg.

Smiles

Cl.O=C(C1=CC(O)=CC=C1OCC(O)CNCCC)CCC=2C=CC=CC2

Molecular Formula

C21H28ClNO4

Molecular Weight

393.9

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/351432388615602248/T207763

CAS Number

86383-32-6

Available Sizes

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