Orexin 2 Receptor Agonist 3
Product Specifications
Target
OX Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
Orexin 2 Receptor Agonist 3 is an orally active and brain-penetrant agonist of the orexin receptor 2 (OX2) with an EC50 value of 2.5 nM. This compound increases wakefulness in both orexin/ataxin-3 NT1 mouse models and healthy Beagle dogs. It is applicable for research related to narcolepsy.
Smiles
FC1=C([C@H](C(NC2(C3)CC3(C)C2)=O)N(C4CC5(CC5)C4)C(CC6=C(C7=NN(C)N=N7)ON=C6)=O)C=C(F)C=C1
Molecular Formula
C27H29F2N7O3
Molecular Weight
537.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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