What is the catalog number for TRPV1 antagonist 11?

The catalog number for TRPV1 antagonist 11 is T207739.

What sizes are available for TRPV1 antagonist 11?

TRPV1 antagonist 11 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does TRPV1 antagonist 11 come in?

TRPV1 antagonist 11 is available in 2 different pack sizes.

Is TRPV1 antagonist 11 in stock?

TRPV1 antagonist 11 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TRPV1 antagonist 11?

TRPV1 antagonist 11 is manufactured by Molfinity.

What is the estimated delivery time for TRPV1 antagonist 11?

Estimated delivery time for TRPV1 antagonist 11 is approximately 10 business day(s), depending on your location.

TRPV1 antagonist 11

Product Specifications

Target

Opioid Receptor, TRP/TRPV Channel

Related Pathways

Membrane transporter/Ion channel, Neuroscience, Endocrinology/Hormones, GPCR/G Protein

Bioactivity

TRPV1 antagonist 11 (compound 2ac) is a highly potent TRPV1 antagonist with an IC50 of 29.3 nM. It also acts as a μ-opioid receptor (MOR) agonist with a Ki of 60.3 nM. This pyrimidinylpiperazine compound provides analgesic effects by antagonizing TRPV1 and activating MOR. In mouse models of formalin-induced pain, TRPV1 antagonist 11 demonstrates effective dose-dependent antinociceptive properties.