6-Thio-GTP tetrasodium
Product Specifications
Target
Ras
Related Pathways
MAPK, GPCR/G Protein
Bioactivity
6-Thio-GTP (tetrasodium) is an inhibitor of Vav1-Rac. It can suppress TCR-induced T cell proliferation and CD28-mediated T cell survival. In a murine model of allogeneic heart transplantation, 6-Thio-GTP (tetrasodium) demonstrates immunosuppressive effects, which can prolong the survival time of heart transplants.
Molecular Formula
C10H12N5Na4O13P3S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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