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6-Thio-GTP tetrasodium

Product Specifications

Target

Ras

Related Pathways

MAPK, GPCR/G Protein

Bioactivity

6-Thio-GTP (tetrasodium) is an inhibitor of Vav1-Rac. It can suppress TCR-induced T cell proliferation and CD28-mediated T cell survival. In a murine model of allogeneic heart transplantation, 6-Thio-GTP (tetrasodium) demonstrates immunosuppressive effects, which can prolong the survival time of heart transplants.

Molecular Formula

C10H12N5Na4O13P3S

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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