Polθ-IN-8
Product Specifications
CAS Number
3056743-98-4
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Bioactivity
Polθ-IN-8 (example 77) is a DNA polymerase θ (Polθ) inhibitor with an IC50 for Polθ ATPase activity of less than 100 nM. Polθ-IN-8 is useful for researching diseases related to Polθ activity, such as cancer.
Smiles
O=C(NC1=NC=2C=NC(=NC2S1)NCC(O)(C)C)C=3C=NC(=CC3C4=CC(Cl)=NC=C4OC)C
Molecular Formula
C22H22ClN7O3S
Molecular Weight
499.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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