S-15176
Product Specifications
CAS Number
148089-70-7
Target
Mitochondrial Metabolism
Related Pathways
Metabolism
Bioactivity
S-15176 is an inhibitor of the mitochondrial permeability transition pore (PTP) . It effectively suppresses mitochondrial swelling induced by tert-butyl hydroperoxide, with an IC50 value of 45.7 ?M. S-15176 prevents the opening of PTP, thus averting the dissipation of mitochondrial membrane potential and the oxidation of NAD (P) H, while enhancing mitochondrial calcium loading capacity. It holds potential for research into ischemia-reperfusion injury.
Smiles
OC=1C(=CC(SCCCN2CCN(CC3=CC=C(OC)C(OC)=C3OC)CC2)=CC1C(C)(C)C)C(C)(C)C
Molecular Formula
C31H48N2O4S
Molecular Weight
544.79
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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