TRPC6 antagonist-1
Product Specifications
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
TRPC6 antagonist-1 (X26) is a TRPC6 inhibitor with IC50 values of 0.97 μM for TRPC6, 3.93 μM for TRPC3, 5.77 μM for TRPC5, and 4.37 μM for TRPC7. Additionally, TRPC6 antagonist-1 hinders TGF-β1-induced myofibroblast differentiation, thereby mitigating renal fibrosis.
Molecular Formula
C26H32N4O2S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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