What is the catalog number for EGFR-IN-158?

The catalog number for EGFR-IN-158 is T207640.

What sizes are available for EGFR-IN-158?

EGFR-IN-158 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does EGFR-IN-158 come in?

EGFR-IN-158 is available in 2 different pack sizes.

Is EGFR-IN-158 in stock?

EGFR-IN-158 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFR-IN-158?

EGFR-IN-158 is manufactured by Molfinity.

What is the estimated delivery time for EGFR-IN-158?

Estimated delivery time for EGFR-IN-158 is approximately 10 business day(s), depending on your location.

EGFR-IN-158

Product Specifications

Target

Apoptosis, EGFR

Related Pathways

JAK/STAT signaling, Apoptosis, Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

EGFR-IN-158 (compound 12e) is an orally active EGFR inhibitor with an IC50 value of 0.22 nM for EGFR (Del19/T790M) . By binding to EGFR, EGFR-IN-158 inhibits phosphorylation and downstream signaling, thereby suppressing the proliferation of tumor cell lines and promoting apoptosis.