AL-34662 formate

AL-34662 (formate) is a 5-HT2 receptor agonist with an IC50 of 0.8-1.5 nM. It stimulates phosphoinositol turnover and Ca2+ release in human ciliary muscle cells (h-CM) with an E50 of 289 nM and in human trabecular meshwork cells (h-TM) with an E50 of 254 nM. It is used in research on reducing intraocular pressure (IOP) .