What is the catalog number for TrxR-IN-8?

The catalog number for TrxR-IN-8 is T207620.

What sizes are available for TrxR-IN-8?

TrxR-IN-8 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does TrxR-IN-8 come in?

TrxR-IN-8 is available in 2 different pack sizes.

Is TrxR-IN-8 in stock?

TrxR-IN-8 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TrxR-IN-8?

TrxR-IN-8 is manufactured by Molfinity.

What is the estimated delivery time for TrxR-IN-8?

Estimated delivery time for TrxR-IN-8 is approximately 10 business day(s), depending on your location.

TrxR-IN-8

Product Specifications

CAS Number

2857180-28-8

Target

Apoptosis, Reactive Oxygen Species

Related Pathways

Metabolism, NF-κB, Apoptosis, Immunology/Inflammation

Bioactivity

TrxR-IN-8 (Compound 6f) is a selective inhibitor of TrxR with an IC50 of 10.2 μM. It induces apoptosis through oxidative stress by stimulating the production of reactive oxygen species, reducing intracellular thiols, and lowering the glutathione/glutathione disulfide ratio. TrxR-IN-8 exhibits significant cytotoxicity against non-small cell lung cancer (NSCLC) cells.