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(1S,2R,7S) -Sitafloxacin

Product Specifications

CAS Number

127254-11-9

Target

Topoisomerase, Antibacterial, Antibiotic

Related Pathways

Microbiology/Virology, DNA Damage/DNA Repair

Bioactivity

(1S,2R,7S) -Sitafloxacin (DU-6856) is an enantiomer of Sitafloxacin and functions as a topoisomerase inhibitor. As an antibiotic, it demonstrates inhibitory activity against Escherichia coli DNA gyrase (IC50 0.18 μg/mL) and Staphylococcus aureus topoisomerase IV. (1S,2R,7S) -Sitafloxacin exhibits antibacterial properties and is utilized in the study of various bacterial infections.

Smiles

N[C@H]1C2(CN(C1)C=3C(Cl)=C4N(C=C(C(O)=O)C(=O)C4=CC3F)[C@@H]5[C@H](F)C5)CC2

Molecular Formula

C19H18ClF2N3O3

Molecular Weight

409.81

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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