PPA-037
Product Specifications
CAS Number
2883700-83-0
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
PPA-037 is an orally active and highly selective inhibitor of cyclin-dependent kinase 12 (CDK12) . It induces the degradation of Cyclin K, thereby enhancing antiproliferative effects on tumor cells. PPA-037 holds potential for use in cancer research.
Smiles
N(CC1=CC=C(C=C1)C2=CC=CC=N2)C=3N4C(=C(C=N4)C5CC5)N=C(N[C@H]6CCNC6)C3
Molecular Formula
C25H27N7
Molecular Weight
425.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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