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ER? degrader 13

Product Specifications

CAS Number

3070968-56-5

Target

Estrogen Receptor/ERR

Related Pathways

Endocrinology/Hormones

Bioactivity

ER? degrader13 (compound MR3) is a potent ER? degrader with an IC50 of 0.55 ?M. It demonstrates significant tumor regression effects in a breast cancer xenograft mouse model.

Smiles

C(=O)(C1=C(SC=2C1=CC=C(O)C2)C3=CC=C(O)C=C3)C4=CC=C(OCCNC(CCCCCC/N=C/5\C=6C(C=7C(=C5)SC=8C(N7)=CC=C(N(CC)CC)C8)=CC=CC6)=O)C=C4

Molecular Formula

C50H48N4O5S2

Molecular Weight

849.07

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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