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CB1R Allosteric modulator 5

Product Specifications

CAS Number

3019958-44-9

Target

Cannabinoid Receptor

Related Pathways

GPCR/G Protein

Bioactivity

CB1R Allosteric modulator 5 (compound 3) is a selective allosteric modulator of cannabinoid receptor type 1 (Cannabinoid receptor type 1) that can cross the blood-brain barrier, with a pIC0 value of 6.89. It reduces cue-induced reinstatement of cocaine-seeking behavior and cocaine-induced behavioral sensitization without altering motor activity.

Smiles

O=C1C(=O)C(NCCC=2C=CC=C(Cl)C2)=C1NC3=CC=C(Cl)C=C3

Molecular Formula

C18H14Cl2N2O2

Molecular Weight

361.22

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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