Sibenadet
Product Specifications
CAS Number
154189-40-9
Target
Dopamine Receptor|||Adrenergic Receptor
Related Pathways
Neuroscience|||GPCR/G Protein
Bioactivity
Sibenadet (AR-C68397AA (free base) ) is a dual dopamine D2/?2-adrenoceptor agonist with selectivity for ?2-adrenoceptor activation. It inhibits capsaicin-induced plasma protein extravasation in rat trachea and reduces edema by activating ?2-adrenergic receptors, thereby inhibiting the activation of sensory nerve fibers. Sibenadet is a potential candidate for chronic obstructive pulmonary disease (COPD) research.
Smiles
O=C1SC=2C(=CC=C(O)C2N1)CCNCCS(=O)(=O)CCCOCCC=3C=CC=CC3
Molecular Formula
C22H28N2O5S2
Molecular Weight
464.6
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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