PD-1/PD-L1-IN-55
Product Specifications
CAS Number
3052262-83-3
Target
PD-1/PD-L1
Related Pathways
Immunology/Inflammation|||Cell Cycle/Checkpoint|||Apoptosis
Bioactivity
PD-1/PD-L1-IN-55 (compound D6) is a potent PD-1/PD-L1 inhibitor with an IC50 of 4.8 nM. It enhances IFN-? secretion and decreases the proportion of late apoptosis due to PD-L1.
Smiles
C([C@H](C)N)(=O)N1CC=2C(C1)=CC=C(C2)C3=C(Cl)C(=CC=C3)C=4C=C5C(=CC4)OCCO5
Molecular Formula
C25H23ClN2O3
Molecular Weight
434.92
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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