VU0469650 hydrochloride
Product Specifications
Target
GluR
Related Pathways
Neuroscience
Bioactivity
VU0469650 hydrochloride is a brain-penetrant negative allosteric modulator of the metabotropic glutamate receptor 1 (mGluR1) . It inhibits glutamate-induced calcium flux in cells expressing human mGluR1 with an IC50 of 99 nM. VU0469650 hydrochloride holds potential for research into central nervous system disorders such as anxiety, addiction, and epilepsy.
Molecular Formula
C22H29ClN4O
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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