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VU0469650 hydrochloride

Product Specifications

Target

GluR

Related Pathways

Neuroscience

Bioactivity

VU0469650 hydrochloride is a brain-penetrant negative allosteric modulator of the metabotropic glutamate receptor 1 (mGluR1) . It inhibits glutamate-induced calcium flux in cells expressing human mGluR1 with an IC50 of 99 nM. VU0469650 hydrochloride holds potential for research into central nervous system disorders such as anxiety, addiction, and epilepsy.

Molecular Formula

C22H29ClN4O

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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