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CS-VIP 8

Product Specifications

Target

Histone Methyltransferase|||JAK

Related Pathways

Stem Cells|||Tyrosine Kinase/Adaptors|||Chromatin/Epigenetic|||JAK/STAT signaling|||Angiogenesis

Bioactivity

CS-VIP 8 is a selective allosteric inhibitor of the WDR5 protein (Ki= 0.008 ?M) . It induces conformational changes in the MLL1 complex, causing the dissociation of MLL1 from the complex and inhibiting MLL1 histone methyltransferase activity, thereby regulating HOX gene expression. CS-VIP 8 shows potential for research in hematological diseases such as leukemia.

Molecular Formula

C43H52F4N12O7

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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