DN-108
Product Specifications
CAS Number
195604-21-8
Target
PPAR
Related Pathways
DNA Damage/DNA Repair, Metabolism
Bioactivity
DN-108, a thiazolidinedione derivative, acts as an orally active peroxisome proliferator-activated receptor γ (PPARγ) agonist with antidiabetic properties. It improves hyperglycemia, hypertriglyceridemia, and hyperinsulinemia in diabetic mouse models. DN-108 enhances tissue glucose uptake (e.g., increases 2-deoxyglucose uptake in L6 muscle cells) and inhibits fatty acid synthase activity, making it a promising candidate for type 2 diabetes research.
Smiles
O=C1SC(C(=O)N1)CC2=CC=C(C=C2)NC(=O)C3(C=4C=CC=CC4)CC3
Molecular Formula
C20H18N2O3S
Molecular Weight
366.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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