FGFR-IN-19
Product Specifications
Target
FGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
Arg-IN-1 is a selective covalent inhibitor targeting Arginine (Arg), with IC50 values of 9.7 nM and 30.4 nM for FGFR2 and FGFR3, respectively. This compound is designed to potentially avoid the off-target toxicity of FGFR1/4 and overcome acquired resistance, offering potential in cancer therapies targeting FGFR.
Molecular Formula
C36H42N12O6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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