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FGFR-IN-19

Product Specifications

Target

FGFR

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors

Bioactivity

Arg-IN-1 is a selective covalent inhibitor targeting Arginine (Arg), with IC50 values of 9.7 nM and 30.4 nM for FGFR2 and FGFR3, respectively. This compound is designed to potentially avoid the off-target toxicity of FGFR1/4 and overcome acquired resistance, offering potential in cancer therapies targeting FGFR.

Molecular Formula

C36H42N12O6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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