What is the catalog number for CDK9/HDAC1/HDAC3-IN-1?

The catalog number for CDK9/HDAC1/HDAC3-IN-1 is T207433.

What sizes are available for CDK9/HDAC1/HDAC3-IN-1?

CDK9/HDAC1/HDAC3-IN-1 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does CDK9/HDAC1/HDAC3-IN-1 come in?

CDK9/HDAC1/HDAC3-IN-1 is available in 2 different pack sizes.

Is CDK9/HDAC1/HDAC3-IN-1 in stock?

CDK9/HDAC1/HDAC3-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CDK9/HDAC1/HDAC3-IN-1?

CDK9/HDAC1/HDAC3-IN-1 is manufactured by Molfinity.

What is the estimated delivery time for CDK9/HDAC1/HDAC3-IN-1?

Estimated delivery time for CDK9/HDAC1/HDAC3-IN-1 is approximately 10 business day(s), depending on your location.

CDK9/HDAC1/HDAC3-IN-1

Product Specifications

CAS Number

2197029-81-3

Target

Apoptosis, CDK, HDAC

Related Pathways

Chromatin/Epigenetic, DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Apoptosis

Bioactivity

CDK9/HDAC1/HDAC3-IN-1 is a dual inhibitor targeting CDK9 and HDAC enzymes. It potently suppresses the activity of CDK9, HDAC1, and HDAC3, with IC50 values of 0.17 μM, 1.73 μM, and 1.11 μM, respectively. The compound inhibits cancer cell growth by inducing apoptosis and causing cell cycle arrest at the G2/M phase. In a mouse model using TNBC MDA-MB-231 xenografts, it effectively hinders tumor progression. This compound exhibits broad-spectrum anticancer effects, notably against breast cancer, cervical cancer, and liver cancer.