BS-153
Product Specifications
CAS Number
1935692-54-8
Target
NF-κB
Related Pathways
NF-κB
Bioactivity
BS-153 is a novel synthetic oxazolidinone drug that exhibits anti-inflammatory effects by blocking the activation of the NF-κB/PKCθ pathway. It can suppress the expression levels of iNOS, COX-2, and pro-inflammatory cytokines (TNF-α, IL-1β, and IL-6) in LPS-stimulated RAW264.7 cells.
Smiles
N#CC1=CC(=CC=C1N2CCC(N3CCOCC3)CC2)C(=O)NC=4C=NN(C5=CC=C(Cl)C=C5)C4C(F)(F)F
Molecular Formula
C27H26ClF3N6O2
Molecular Weight
558.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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