Amyloid-?-IN-2
Product Specifications
CAS Number
1603833-55-1
Target
Beta Amyloid|||Gamma-secretase
Related Pathways
Neuroscience|||Stem Cells|||Proteases/Proteasome
Bioactivity
Amyloid-?-IN-2 (Compound EX.112) is a selective inhibitor of ?-secretase. In H4 cells, it demonstrates inhibitory activity on A?42 secretion, with an EC50 value of 226 nM. Amyloid-?-IN-2 holds potential for research in Alzheimer's disease (AD) and diseases associated with A? deposition.
Smiles
C(NC1=CC(F)=CC(F)=C1)(=O)C2=CC=3C(N2)=CC=C(C3)[C@@H]4CN(C(C)=O)CCC4
Molecular Formula
C22H21F2N3O2
Molecular Weight
397.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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