FGT-4
Product Specifications
Target
TLR, PROTACs, NO Synthase
Related Pathways
PROTAC, Immunology/Inflammation
Bioactivity
FGT-4 is a chimeric molecule targeting folate receptor β (FR-β) and functions as a TLR7 agonist. It enhances the secretion of iNOS and the pro-inflammatory cytokine IL-6 associated with M1 macrophages and promotes the proliferation of cytotoxic CD8+ T cells. FGT-4 demonstrates antitumor activity in the 4T1 breast cancer mouse model and is applicable for cancer immunotherapy research.
Molecular Formula
C50H57N11O9S2
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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