What is the catalog number for CW-2?

The catalog number for CW-2 is T207351.

What sizes are available for CW-2?

CW-2 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does CW-2 come in?

CW-2 is available in 2 different pack sizes.

CW-2 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CW-2?

CW-2 is manufactured by Molfinity.

What is the estimated delivery time for CW-2?

Estimated delivery time for CW-2 is approximately 10 business day(s), depending on your location.

CW-2

Product Specifications

Target

PARP, PROTACs, DNA/RNA Synthesis

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Chromatin/Epigenetic, PROTAC

Bioactivity

CW-2 is a PARP1 PROTAC degrader known for its potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and cisplatin-resistant cells (A549/CDDP: IC50 = 3.52 μM) . It exhibits synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts its antitumor effects by inducing DNA damage, disrupting DNA repair, and triggering mitochondrial-dependent apoptosis (apoptosis) .