What is the catalog number for CLK2/3-IN-1?

The catalog number for CLK2/3-IN-1 is T207346.

What sizes are available for CLK2/3-IN-1?

CLK2/3-IN-1 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does CLK2/3-IN-1 come in?

CLK2/3-IN-1 is available in 2 different pack sizes.

Is CLK2/3-IN-1 in stock?

CLK2/3-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CLK2/3-IN-1?

CLK2/3-IN-1 is manufactured by Molfinity.

What is the estimated delivery time for CLK2/3-IN-1?

Estimated delivery time for CLK2/3-IN-1 is approximately 10 business day(s), depending on your location.

CLK2/3-IN-1

Product Specifications

Target

CDK

Related Pathways

Cell Cycle/Checkpoint

Bioactivity

CLK2/3-IN-1 (Compound 7c) is an orally active inhibitor of CLK2/3, with EC50 values of 5.07 nM and 30.03 nM, respectively. Its inhibitory action is facilitated by hydrogen bonding with Lys193 and Lys186 residues of CLK2/3. This compound effectively inhibits the proliferation of SW480 tumor cells with an IC50 of 163 nM and is applicable for research into CLK-related cancer diseases.