CLK2/3-IN-1
Product Specifications
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
CLK2/3-IN-1 (Compound 7c) is an orally active inhibitor of CLK2/3, with EC50 values of 5.07 nM and 30.03 nM, respectively. Its inhibitory action is facilitated by hydrogen bonding with Lys193 and Lys186 residues of CLK2/3. This compound effectively inhibits the proliferation of SW480 tumor cells with an IC50 of 163 nM and is applicable for research into CLK-related cancer diseases.
Molecular Formula
C24H25N7O
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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