What is the catalog number for (3S) -Tanzisertib hydrochloride?

The catalog number for (3S) -Tanzisertib hydrochloride is T207342.

What sizes are available for (3S) -Tanzisertib hydrochloride?

(3S) -Tanzisertib hydrochloride is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does (3S) -Tanzisertib hydrochloride come in?

(3S) -Tanzisertib hydrochloride is available in 2 different pack sizes.

Is (3S) -Tanzisertib hydrochloride in stock?

(3S) -Tanzisertib hydrochloride is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures (3S) -Tanzisertib hydrochloride?

(3S) -Tanzisertib hydrochloride is manufactured by Molfinity.

What is the estimated delivery time for (3S) -Tanzisertib hydrochloride?

Estimated delivery time for (3S) -Tanzisertib hydrochloride is approximately 10 business day(s), depending on your location.

(3S) -Tanzisertib hydrochloride

Product Specifications

CAS Number

2517855-91-1

Target

P38 MAPK, ERK, JNK, EGFR, TNF

Related Pathways

MAPK, Apoptosis, Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors

Bioactivity

(3S) -Tanzisertib (hydrochloride) ((3S) -CC-930 (hydrochloride) ) is an orally active JNK inhibitor, exhibiting IC50 values of 61 nM for JNK1, 7 nM for JNK2, and 6 nM for JNK3. It selectively inhibits ERK1, p38α, and EGFR, with IC50 values of 0.48 μM, 3.4 μM, and 0.38 μM, respectively. In an acute rat PK-PD model, (3S) -Tanzisertib (hydrochloride) suppresses LPS-induced TNFα production and is utilized in research on idiopathic pulmonary fibrosis (IPF) .