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SPP-037

Product Specifications

Target

Endogenous Metabolite, FAK

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis, Metabolism, Cytoskeletal Signaling

Bioactivity

SPP-037 is an orally active selective inhibitor of ST6GAL1, with an IC50 of 3.59 μM. It exhibits anti-migration activity against MDA-MB-231 cells by inhibiting integrin α2,6-sialylation and the integrin-FAK-paxillin pathway. In MDA-MB-231 xenograft mouse models, SPP-037 demonstrates antitumor properties. This compound is applicable in breast cancer research.

Molecular Formula

C36H50ClN3O9S

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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