RIPK3-IN-5

RIP kinase, Necroptosis

Apoptosis, NF-κB

RIPK3-IN-5 (compound 32) is a potent RIPK3 inhibitor with an IC50 of 27 nM. Additionally, it inhibits necroptosis with an EC50 of 0.45 μM.

FC(C=CC=C1F)=C1NC2=NC=NC3=CC(C4=CN=C(N5CCN(C)CC5)C=C4)=CC=C32

C24H22F2N6

432.47

Ice Packs

-20°C