RIPK3-IN-5
Product Specifications
Target
RIP kinase, Necroptosis
Related Pathways
Apoptosis, NF-κB
Bioactivity
RIPK3-IN-5 (compound 32) is a potent RIPK3 inhibitor with an IC50 of 27 nM. Additionally, it inhibits necroptosis with an EC50 of 0.45 μM.
Smiles
FC(C=CC=C1F)=C1NC2=NC=NC3=CC(C4=CN=C(N5CCN(C)CC5)C=C4)=CC=C32
Molecular Formula
C24H22F2N6
Molecular Weight
432.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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