JAK3-IN-17
Product Specifications
Target
JAK
Related Pathways
Stem Cells|||JAK/STAT signaling|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors|||Angiogenesis
Bioactivity
JAK3-IN-17 is an orally active JAK3 inhibitor with an IC50 of 14.56 nM. It demonstrates anti-inflammatory activity by inhibiting the production of IL-2 and IL-6 in a DNCB-induced mouse model of atopic dermatitis.
Smiles
FC1=NC=CC=C1C(C=C2)=CN3C2=NC=C3C4=CC(NC(C=C)=O)=CC=C4
Molecular Formula
C21H15FN4O
Molecular Weight
358.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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