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ZS3-046

Product Specifications

Target

MDM-2/p53, PROTACs

Related Pathways

PROTAC, Apoptosis

Bioactivity

ZS3-046 is a TAF1 PROTAC degrader that facilitates the ubiquitination and subsequent degradation of TAF1. It can activate p53 and induce apoptosis in acute myeloid leukemia (AML) cells. Additionally, ZS3-046 demonstrates anti-tumor efficacy in AML xenograft mouse models.

Molecular Formula

C49H57N9O7

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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