3'-Hydroxy simvastatin

1283861-33-5

Drug Metabolite

Metabolism

3'-Hydroxy simvastatin is a metabolite of Simvastatin, an orally active competitive inhibitor of HMG-CoA reductase (HMGCR) with a Ki of 0.2 nM.

O(C(C(C(C)O)(C)C)=O)[C@@H]1[C@]2(C(C=C[C@H](C)[C@@H]2CC[C@@H]3C[C@@H](O)CC(=O)O3)=C[C@H](C)C1)[H]

C25H38O6

434.57

Cool pack

-20°C