ERK2-IN-6
Product Specifications
CAS Number
2095713-33-8
Target
ERK
Related Pathways
MAPK
Bioactivity
ERK2-IN-6 (Compound 20) is a highly selective ERK1/2 inhibitor with an IC50 value of 7.9 nM for ERK2. It effectively inhibits the proliferation of BRAFV600E mutant cells, with an IC50 of 250 nM in A375 cells. ERK2-IN-6 shows potential for research in solid tumors such as melanoma with BRAF mutations.
Smiles
O=C1C=2C=C(C=CC2CN1CC(=O)NC(C=3C=CC=CC3)(C)C)C4=NC(=NC=C4Cl)NC5CCOCC5
Molecular Formula
C28H30ClN5O3
Molecular Weight
520.02
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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