JNN-5
Product Specifications
Target
JAK
Related Pathways
JAK/STAT signaling, Angiogenesis, Stem Cells, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors
Bioactivity
JNN-5 is an effective JAK2 selective inhibitor with an IC50 of 0.41 nM. It demonstrates strong antiproliferative activity in TNBC cell lines [MDA-MB-468, MDA-MB-213, HCC70, MDA-MB-157].
Smiles
CC1=C(C2=CN(C(C)C)N=C2)N=C(NC3=CC(CCN(C(/C=C/C(C4=CC=C(Cl)C=C4)=O)=O)C5)=C5C=C3)N=C1
Molecular Formula
C30H29ClN6O2
Molecular Weight
541.04
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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