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NSC177365

Product Specifications

CAS Number

80261-18-3

Target

Antibacterial

Related Pathways

Microbiology/Virology

Bioactivity

NSC177365 (NSC 1) is a CcrM inhibitor and acts as a competitive DNA inhibitor that disrupts DNA binding. It exhibits antibacterial activity with IC50 values of 2.3 ?M against Caulobacter crescentus (C. crescentus) and 14.6 ?M against M. lincolnii. Additionally, NSC177365 has the potential to reverse various neurodegenerative diseases and serves as an anticancer agent.

Smiles

O=S(NC(C=C1)=CC=C1NC2=C3C=CC([N+]([O-])=O)=CC3=NC4=C2C=CC=C4)(CCCNC(N)=N)=O

Molecular Formula

C23H23N7O4S

Molecular Weight

493.54

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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