NSC177365
Product Specifications
CAS Number
80261-18-3
Target
Antibacterial
Related Pathways
Microbiology/Virology
Bioactivity
NSC177365 (NSC 1) is a CcrM inhibitor and acts as a competitive DNA inhibitor that disrupts DNA binding. It exhibits antibacterial activity with IC50 values of 2.3 ?M against Caulobacter crescentus (C. crescentus) and 14.6 ?M against M. lincolnii. Additionally, NSC177365 has the potential to reverse various neurodegenerative diseases and serves as an anticancer agent.
Smiles
O=S(NC(C=C1)=CC=C1NC2=C3C=CC([N+]([O-])=O)=CC3=NC4=C2C=CC=C4)(CCCNC(N)=N)=O
Molecular Formula
C23H23N7O4S
Molecular Weight
493.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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