GSK-3? inhibitor 27
Product Specifications
Target
Beta Amyloid|||GSK-3
Related Pathways
Neuroscience|||PI3K/Akt/mTOR signaling|||Stem Cells
Bioactivity
GSK-3? inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3? with an IC50 value of 2.2 ?M. It inhibits tau hyperphosphorylation and reduces A? protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3? inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.
Smiles
ClC1=CC=C(CN(C(/C=C\C(NC2=NNC(C)=C2)=O)=O)C)C=C1
Molecular Formula
C16H17ClN4O2
Molecular Weight
332.79
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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