PDE4B-IN-4
Product Specifications
Target
PDE, TNF
Related Pathways
Apoptosis, Metabolism
Bioactivity
PDE4B-IN-4 is an inhibitor of PDE4B (IC50: 2.82 nM) and TNF-α (IC50: 7.20 nM) . It demonstrates anti-inflammatory properties by reducing neutrophilia in a mouse model of lipopolysaccharide (LPS) -induced sepsis.
Smiles
O=C1NC(N/N=C/C2=CC=C(OC)C(OC)=C2)=NC(C3=CC(OC4CCCC4)=C(OC)C=C3)=C1C#N
Molecular Formula
C26H27N5O5
Molecular Weight
489.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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