Carbonic anhydrase inhibitor 33
Product Specifications
Target
Apoptosis|||Carbonic Anhydrase|||CDK
Related Pathways
Cell Cycle/Checkpoint|||Metabolism|||Apoptosis
Bioactivity
Carbonic anhydrase inhibitor33 (11D) is a dual inhibitor that targets both CA (carbonic anhydrase) IX/XII and CDK6. It exhibits Ki values of 19.7 nM for hCA IX and 26.1 nM for hCA XII. Additionally, Carbonic anhydrase inhibitor33 (11D) can induce G1 phase cell cycle arrest and apoptosis, making it relevant for research in non-small cell lung cancer (NSCLC) .
Molecular Formula
C19H15FN6O2S
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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