What is the catalog number for FLY26?

The catalog number for FLY26 is T207202.

What sizes are available for FLY26?

FLY26 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does FLY26 come in?

FLY26 is available in 2 different pack sizes.

FLY26 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures FLY26?

FLY26 is manufactured by Molfinity.

What is the estimated delivery time for FLY26?

Estimated delivery time for FLY26 is approximately 10 business day(s), depending on your location.

FLY26

Product Specifications

Target

Reactive Oxygen Species, Trk receptor, iGluR

Related Pathways

Neuroscience, Metabolism, Tyrosine Kinase/Adaptors, NF-κB, Membrane transporter/Ion channel, Immunology/Inflammation

Bioactivity

FLY26 is a selective partial antagonist of GluN2B, with an IC50 value of 0.64 μM. FLY26 inhibits the GluN2B subunit of NMDA receptors, reducing calcium ion influx and reactive oxygen species (ROS) production. It also activates the BDNF/TrkB/CREB neuroprotective signaling pathway, mitigating excitotoxicity and mitochondrial dysfunction. FLY26 holds potential for treating neurological deficits caused by cerebral ischemia-reperfusion injury.