Rho GTPase inhibitor 1
Product Specifications
CAS Number
1309252-99-0
Target
Ras
Related Pathways
GPCR/G Protein, MAPK
Bioactivity
Rho GTPase inhibitor 1 (compound 7) is a potent inhibitor of Rho GTPase. It exhibits high affinity for Cdc42, Rac1, and RhoA, with dissociation constants (KDs) of 151 μM, 352 μM, and 232 μM, respectively. Additionally, Rho GTPase inhibitor 1 reduces cell migration in glioblastoma cell lines.
Smiles
N1=CC=2C=CC=CC2C(=C1)C3=CC=CC4=C3OC(CN)C4
Molecular Formula
C18H16N2O
Molecular Weight
276.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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